Single-nucleus RNA Sequencing of Cardiac Tissues in Relation to Antipsychotic Medication Use

Zenodo (CERN European Organization for Nuclear Research) 2026 Dataset Open access

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Authors: Liliang Li
DOI: 10.5281/zenodo.18285734
Cited by: 0

Abstract

We generated a single-nucleus transcriptomic atlas of the human heart to characterize its cellular landscape. By performing a comparative analysis between individuals with a history of antipsychotic medication use and antipsychotic-naïve controls, we identified cell-type-specific transcriptional alterations associated with antipsychotic exposure.

Fields of Study & Subjects

Single-cell and spatial transcriptomics Cardiac electrophysiology and arrhythmias Schizophrenia research and treatment

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
18 January 2026
Document type
Dataset