AAB-seq: Processed single-cell transcriptomic and antigen-affinity BCR sequencing data
Abstract
This repository contains processed data and analysis scripts for AAB-seq (Antigen-Affinity BCR sequencing), a framework for jointly profiling B-cell receptor (BCR) features and single-cell transcriptomes. This Zenodo record provides downstream, analysis-ready resources to support reproducibility and reuse, including: Contents Cell Ranger–derived UMI count matrices Processed single-cell RNA-seq data in .h5ad format Python notebooks and scripts used for preprocessing, quality control, and downstream analyses These data support the analyses presented in the AAB-seq study and enable re-analysis, benchmarking, and methodological extension. Related data Raw FASTQ files: deposited in GEO (accession provided in the associated manuscript doi.org/10.1101/2024.08.13.607736) This record serves as a companion archive to the primary sequencing repository, ensuring transparency and long-term accessibility of processed data and code.
Fields of Study & Subjects
Single-cell and spatial transcriptomics
T-cell and B-cell Immunology
Monoclonal and Polyclonal Antibodies Research
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 18 January 2026
- Document type
- Dataset