Cytomegalovirus Colitis in a Patient Living with HIV: Review of Pathogenic Mechanisms, Diagnosis, and Therapeutic Approach

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Authors: Hachad Salma, Jebbar Sanaa, Inas Ouggane, Hanane Badi, Ihbibane Fatima, Ahd Ouladlahsen, M. Sodqi, Latifa Marih
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Abstract

Cytomegalovirus (CMV) colitis is a serious and potentially fatal complication in patients living with human immunodeficiency virus (HIV), particularly those with severe immunosuppression. CMV, a virus belonging to the Herpesviridae family, takes advantage of immunosuppression to reactivate, leading to various clinical manifestations, including colitis. We report the clinical case of an HIV-positive patient with CMV colitis confirmed by colonic biopsy. This article explores the epidemiological, pathophysiological, clinical, diagnostic and therapeutic aspects of CMV colitis in HIV-positive patients, based on bibliographical references.

Fields of Study & Subjects

Cytomegalovirus and herpesvirus research Herpesvirus Infections and Treatments Viral-associated cancers and disorders

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
19 January 2026
Language
EN