Candida auris: An Emerging Multidrug-Resistant Pathogen Alarming Highest Level of Concern, Case Series

Candida auris is an emerging multidrug-resistant fungus that causes life-threatening healthcare-associated infections. This fungal pathogen has been designated as an urgent threat by the US Centers for Disease Control and Prevention and classified in the Critical Priority group by the World Health Organization. In this report, we describe three cases of nosocomial fungemia caused by C. auris. All three patients exhibited persistent fungemia for approximately 10 to 31 days after their admission to our hospital. We collected patient history and samples for our study. Blood samples were sent to the microbiology laboratory for processing. The isolates obtained were identified as C. auris through MALDI-TOF MS. Antifungal sensitivity testing was conducted using the VITEK-2 compact. All three isolates were found to be pan-resistant to these antifungal agents. Tragically, all three cases resulted in fatal outcomes. The pan-resistance to available therapeutic options is concerning in the hospital and necessitates prompt management