FORMULATION AND EVALUATION OF SILVER NANOPARTICLES USING AQUEOUS EXTRACT OF LANTANA CAMARA FRESH LEAVES

The aim of this study was to investigate the effectiveness of a strategy based on the development of Silver Nanoparticles as an innovative formulation of Lantana camara extract with improved therapeutic efficacy. Lantana camara Silver Nanoparticles were prepared by green synthesis. FTIR studies indicated no interaction between Extract and excipients. Silver nanoparticles were characterized for particle size, zeta potential, entrapment efficiency and surface morphology. In vitro drug release studies were performed in phosphate buffer of pH 7.4 using diffusion technique. The F5 batch had shown maximum entrapment up to 85.55 % and sustained drug release for 8 h. The scanning electron microscopy and zeta potential study showed formation of good Silver nanoparticles dispersion. The stability study showed successful formation of stable silver nanoparticles. Key words: Lantana camara, silver nanoparticles, Green synthesis technique, FTIR, in-vitro drug release.