Functional noncoding variants within TBX1 enhancer contribute to Tetralogy of Fallot
Abstract
This dataset contains single-cell RNA-sequencing (scRNA-seq) and chromatin immunoprecipitation sequencing (ChIP-seq) data generated from human embryonic stem cell (hESC)–derived vascular organoids. Vascular organoids were differentiated from wild-type (WT) and TBX1 enhancer-deleted hESC lines and collected at four developmental stages (Day 0, Day 5, Day 10, and Day 15) to model early human vascular lineage specification and maturation in vitro.
Fields of Study & Subjects
Congenital heart defects research
Congenital Heart Disease Studies
Cardiac electrophysiology and arrhythmias
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 10 February 2026
- Language
- EN
- Document type
- Dataset