What are the potential interactions or side effects of methotrexate when administered to a patient receiving chemotherapy for a different condition?
Abstract
Methotrexate exhibits potential interactions with drugs through transporter-mediated pathways and shares cumulative toxicities with other chemotherapeutic agents, warranting careful monitoring in polytherapy settings.
Fields of Study & Subjects
Drug Transport and Resistance Mechanisms
Pharmacogenetics and Drug Metabolism
Pharmacovigilance and Adverse Drug Reactions
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 20 January 2026