What are the potential interactions or side effects of methotrexate when administered to a patient receiving chemotherapy for a different condition?

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Authors: Tripdatabase
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Abstract

Methotrexate exhibits potential interactions with drugs through transporter-mediated pathways and shares cumulative toxicities with other chemotherapeutic agents, warranting careful monitoring in polytherapy settings.

Fields of Study & Subjects

Drug Transport and Resistance Mechanisms Pharmacogenetics and Drug Metabolism Pharmacovigilance and Adverse Drug Reactions

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
20 January 2026