Dynamic Foundations of Disease IV Physiology as Temporal Stability Autonomic regulation, rhythms, variability, and recovery
Abstract
This paper reframes physiology as a temporal phenomenon rather than a collection of static values. It argues that autonomic regulation, biological rhythms, adaptive variability, and recovery capacity constitute the primary markers of system stability in health and disease. By integrating insights from autonomic physiology, circadian biology, treatment timing, and recovery dynamics, the paper establishes temporal stability as a foundational dimension of disease behavior. It serves as an entry point into a dynamic systems interpretation of medicine, showing how loss of rhythm, altered variability, and delayed recovery often precede structural pathology and conventional biomarker change.
Fields of Study & Subjects
Heart Rate Variability and Autonomic Control
Circadian rhythm and melatonin
Ecosystem dynamics and resilience
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 22 January 2026
- Language
- EN
- Document type
- Preprint