Multi-omic single-nucleus ATAC-seq + RNA-seq of nuclei from the post-mortem human primary motor cortex from patients with ALS, ALS-FTD, C9ORF72-ALS-FTD and neurologically unaffected controls

Veselin Grozdanov; Karin M. Danzer

doi:10.5281/zenodo.18370645

Multi-omic single-nucleus ATAC-seq + RNA-seq of nuclei from the post-mortem human primary motor cortex from patients with ALS, ALS-FTD, C9ORF72-ALS-FTD and neurologically unaffected controls

Zenodo (CERN European Organization for Nuclear Research) 2026 Dataset Open access

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Authors: Veselin Grozdanov, Karin M. Danzer

DOI: 10.5281/zenodo.18370645

Cited by: 0

Abstract

This dataset comprises single-nucleus multi-omic (ATAC-seq + RNA-seq in the same nucleus) data from nuclei purified from the post-mortem human primary motor cortex (M1) from patients with ALS, ALS-FTD, C9ORF72-ALS-FTD and neurologically unaffected controls. Detailed methods and study description in the accompanying publication (tba).

Fields of Study & Subjects

Amyotrophic Lateral Sclerosis Research Single-cell and spatial transcriptomics Alzheimer's disease research and treatments

Publication details

Journal / source: Zenodo (CERN European Organization for Nuclear Research)
Publication date: 29 January 2026
Language: EN
Document type: Dataset