Single-nucleus RNA-seq of human post-mortem primary motor cortex (M1) nuclei from ALS-FTD patients, NeuN+ (neuronal) and sorted for TDP-43 low vs. high signal

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Authors: Veselin Grozdanov, Karin M. Danzer
Cited by: 0

Abstract

This dataset comprises single-nucleus transcriptomic (RNA-seq) data from nuclei purified from the post-mortem human primary motor cortex (M1) from patients with ALS-FTD, after sorting for TDP-43 nuclear signal (NeuN+, TDP-43 low vs. high). Detailed methods and study description in the accompanying publication (tba).

Fields of Study & Subjects

Amyotrophic Lateral Sclerosis Research Single-cell and spatial transcriptomics Alzheimer's disease research and treatments

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
29 January 2026
Language
EN
Document type
Dataset