Scripts for Telomeric Motif and GC Landscape Analysis in Human Genomes

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Authors: Tamalika Manna, Dr. Shankar Prasad Das
Cited by: 0

Abstract

This Zenodo record provides Python and shell scripts used to analyze telomeric and subtelomeric regions in the human reference genomes GRCh38.p14 and T2T-CHM13v2.0. The workflow extracts chromosome ends, identifies telomeric motifs, measures motif continuity and gaps, computes GC concentration, and generates publication-quality figures. These scripts were developed for a study submitted to Nucleic Acids Research.

Fields of Study & Subjects

Chromosomal and Genetic Variations Telomeres Telomerase and Senescence Genomics and Chromatin Dynamics

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
27 January 2026
Language
EN