GATA factors are pioneer-type lineage commitment factors in the human embryo.

Zenodo (CERN European Organization for Nuclear Research) 2026 Preprint Open access

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Authors: Shahan Mamoor
DOI: 10.5281/zenodo.18394984
Cited by: 0

Abstract

We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here discovery of GATA3 as a lineage commitment factor in embryonic stem cells of the human embryo.

Fields of Study & Subjects

Pluripotent Stem Cells Research Developmental Biology and Gene Regulation Genomics and Chromatin Dynamics

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
27 January 2026
Document type
Preprint