Clinical assessment of Probiotic mouthwash as adjunct to non-surgical periodontal therapy in patients with stage II grade A periodontitis

Abstract AIM: To evaluate the effect of probiotic mouthwash with SRP on periodontal indices in patients with stage II, grade A periodontitis. Materials & Methods: Thirty patients were randomly assigned into two groups (n=15) and received SRP treatment along with placebo in one group and probiotic supplementation in the other. After SRP, the test group used probiotic supplemented mouthwash once daily for 21 days. The control group subjects were treated only with SRP. Clinical parameters like PPD, CAL, PI and GI were assessed at baseline, 14 and 21 days. Results: The intra-group analysis using repeated measures ANOVA (Tables 1–4) showed a statistically significant improvement in all periodontal parameters PPD, CAL, PI, and GI across baseline, 14 days, and 21 days in both the probiotic and placebo groups (p < 0.05). The probiotic group demonstrated a greater reduction in PPD from a baseline mean of 6.65 mm to 5.44 mm at 14 days and 4.78 mm at 21 days. PPD showed a significant difference favouring the probiotic group (p = 0.002), while GI showed significant differences at baseline and 14 days (p = 0.049 and 0.014), indicating superior periodontal improvement with probiotic mouthwash. Conclusion – The probiotic supplementation as a mouthwash, along with SRP, had a positive effect on periodontal indices in patients with stage II and grade A generalized periodontitis with the probiotic mouthrinse having a great therapeutic potential. Keywords – Probiotic, Grade A, SRP.