Methylation data for "The DNA methylation landscape of naturally short-lived killifish"

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Authors: Mara Steiger, Nishita Singh, Alexandra M. Tyers, Helene Kretzmer, Dario Riccardo Valenzano, Alexander Meissner
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Abstract

Annual killifish of the genus Nothobranchius are naturally short-lived vertebrates that exhibit a wide range of aging characteristics typically observed in mammals. Here, we provide the first comprehensive whole-genome methylation map for two species, revealing local age-related as well as tissue-specific dynamics in the DNA methylome. Our maps and results add a strong foundation for the annual killifish as a model organism and further highlight its value for studying ageing and making health status predictions in vertebrates. This dataset provides methylation data from WGBS.

Fields of Study & Subjects

Epigenetics and DNA Methylation Genetics Aging and Longevity in Model Organisms Chromosomal and Genetic Variations

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
3 February 2026
Document type
Dataset