Unveiling His835 pKa Shifts and Catalytic Reactivity within a pH-Dependent Local Electrostatic Conformational Landscape across Active and Inactive States of EGFR T790M/L858R and T790M/L858R/C797S Mutants

Zenodo (CERN European Organization for Nuclear Research) 2026 Open access

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Authors: K. Bhanja
DOI: 10.5281/zenodo.18402371
Cited by: 0

Abstract

Constant pH file for all EGFR systems such as DICI, DICO and DOCO conformation.

Fields of Study & Subjects

Lung Cancer Treatments and Mutations Protein Structure and Dynamics HER2/EGFR in Cancer Research

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
28 January 2026