What are the proposed mechanisms by which guselkumab could potentially lead to posterior reversible encephalopathy syndrome (PRES)?

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Authors: Tripdatabase
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Abstract

No direct evidence links guselkumab to PRES, but possible mechanisms may involve modulation of the immune system and endothelial function due to IL-23 inhibition.

Fields of Study & Subjects

Neurological Complications and Syndromes Vasculitis and related conditions Cerebral Venous Sinus Thrombosis

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
28 January 2026