ABOUT OF MECHANISMS OF ANTIBIOTIC RESISTANCE IN PSEUDOMONAS AE-RUGINOSA

Abstract The article analyzes data on the mechanisms of resistance of Pseudomonas aeruginosa to various antibiotics. Pseudomonas aeruginosa has been shown to be an opportunistic pathogen and a leading cause of morbidity and mortality in patients with cystic fibrosis and immunocompromised individuals. Due to their ability to easily adapt to the external environment, Pseudomonas aeruginosa strains are often the cause of healthcare-associated infections. Antibiotic resistance in P. aeruginosa is multifactorial, as it can arise through innate, acquired, or adaptive mechanisms. New therapeutic approaches, such as quorum sensing, phage therapy, and the use of nanoparticles, may have significant antimicrobial effects against antibiotic-resistant strains of P. aeruginosa in vitro.