What are the pharmacokinetic differences between modified-release and immediate-release formulations of metformin?
Abstract
The clinical bottom line is that while pharmacokinetic differences exist between immediate-release and extended-release metformin formulations, both achieve similar systemic drug exposure, which may affect dosing convenience and side effect profiles.
Fields of Study & Subjects
Diabetes Treatment and Management
Pharmacogenetics and Drug Metabolism
Diabetes Management and Research
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 29 January 2026