Operetta Drug Profiling benchmark 10x multiwell plate

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Authors: Fabio D. Steffen, Loredana K. Cantoni
Cited by: 0

Abstract

Example dataset of leukemia cells from a patient-derived xenograft (PDX) model co-cultured with mesenchymal stromal cells. Cells were exposed to a library of drugs (conditions.csv) including standard chemotherapeutics (e.g. vincristine, idarubicin, dexamethasone) and targeted agents (e.g. venetoclax, dasatinib, eltanexor). The cells are stained with a viability dye (CyQuant) and imaged at the PerkinElmer Operetta high-content microscope in 10x magnification. Used for benchmark workflows of the Fractal platform (https://fractal-analytics-platform.github.io/).

Fields of Study & Subjects

Cell Image Analysis Techniques Digital Imaging for Blood Diseases Acute Myeloid Leukemia Research

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
29 January 2026
Document type
Dataset