PHARMACEUTICO – ANALAYTICAL AND IN-VITRO STUDY CYTOTOXIC EFFECT OF MEDHOARBUDAHARA ARKA

Arka Kalpana is a liquid dosage form in Ayurvedic pharmaceutics. Various methods of preparation are mentioned in Arka Prakāśa, depending on the nature of the drugs. However, comparatively few classical references are available regarding Arka preparation. In Arka Prakāśa (6th Śataka), Medoarbudhahara Arka is mentioned under the indication Medoarbuda. In todays practice, many Vaidyas follow the preparation method prescribed in the Ayurvedic Formulary of India (AFI). To compare them, a pharmaceutical, analytical, and in vitro cytotoxicity study was conducted on the MCF-7 and OP9 cell lines. Two batches were prepared: one according to classical references, and the other following the AFI method.