DETERMINING THE ROLE OF MMP-9 AND TIMP-1 POLYMORPHIC GENES IN SARS COV-2 INDUCED MYOCARDITIS.

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Authors: Akhmedova Gulchehra Abdullaevna, Aminov Feruz Ravshanbekovich, Rasulov Rakhmatillo Saydullayevich
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Abstract

Current evidence suggests that MMP and TIMP gene polymorphisms may have a significant impact on the degree of inflammation and structural changes in the myocardium during viral infections, including COVID-19. However, the results of studies remain contradictory due to differences in study groups, methodologies, and evaluation criteria. In addition, most of the studies have focused on general aspects of inflammation in myocarditis, and the exact mechanisms associated with genetic variants in the MMP and TIMP genes are poorly understood.

Fields of Study & Subjects

Viral Infections and Immunology Research COVID-19 Clinical Research Studies Cardiac Fibrosis and Remodeling

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
30 January 2026
Document type
Dataset