Prime Number Harmonics Predict the Helical Periodicities of DNA and Protein α-Helices

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Authors: Patrick Guiffra
Cited by: 0

Abstract

Hello,I investigate a mathematical relationship between the spectral properties of prime number distributions and the geometric periodicities of biological helical structures. By constructing a scalar field Ω(x, q) as a weighted superposition of cosine waves with frequencies determined by modular inverses of prime numbers, we observe that dominant Fourier peaks emerge at wavelengths closely matching known biological structures. For modulus q = 7, we find a harmonic at λ = 3.504 (error 2.68% vs. the canonical α-helix pitch of 3.6 residues/turn). For q = 21, a harmonic appears at λ = 10.511 (error 0.10% vs. B-form DNA’s 10.5 bases/turn). These wavelengths arise from exact arithmetic: λ = q/k where k = p−1 mod q for specific primes p. Notably, the prime p = 11 generates both biological periodicities through its modular inverse 11−1 ≡ 2 in q ∈ {7, 21}. We perform a systematic survey of moduli q ∈ [3, 30] and calculate the statistical significance of these correspondences (p < 0.01). While our results demonstrate a striking numerical correlation, we emphasize that causality remains unestablished. We discuss potential physical mechanisms and propose experimental tests to determine whether this correspondence reflects fundamental biophysical principles or numerical coincidenceCordialy

Fields of Study & Subjects

Advanced Mathematical Theories and Applications Fractal and DNA sequence analysis Analytic Number Theory Research

Publication details

Publication date
30 January 2026
Document type
Preprint