FireGate Biotech FG-002: In Silico Systems Analysis Supporting Viral-Mimicry–Driven Tumor Immune Reprogramming

We performed an in silico systems-level functional association and enrichment analysis usingthe STRING database to assess whether a curated FG-002 viral sensing, interferon signaling,and antigen presentation gene/protein set forms a coherent non-random immune network. Theanalysis demonstrates dense protein–protein interaction connectivity and strong overrepresen-tation of viral response, interferon-associated innate immune programs, and antigen process-ing/presentation pathways. These results support a mechanistic framework in which inductionof viral-mimicry-like signaling may promote tumor immunogenicity and immune engagement.