EVALUATION OF ANTI-DIARRHOEAL AND ANTI-CONSTIPATION EFFECTS OF SAMBUKADI VATI IN EXPERIMENTALLY INDUCED IRRITABLE BOWEL SYNDROME MODELS IN WISTAR RATS

The therapeutic efficacy of Sambukadi Vati, a classical Ayurvedic formulation, was evaluated for its dual action on Grahani Roga, specifically focusing on Irritable bowel syndrome–Diarrhea predominant (IBS-D) and Constipation predominant (IBS-C). Using experimentally induced disease models in Wistar rats, the study assessed parameters such as Bristol stool scale, Faecal water content, loose stool rate, and faecal pellet count. The results demonstrated that Sambukadi Vati significantly regulates bowel motility and intestinal secretion, validating its traditional use in managing functional bowel disorders.