COMPARATIVE EVALUATION OF THE EFFICACY OF PRF, OZONATED OLIVE OIL AND BLUEM GEL APPLICATION ON WOUND HEALING FOLLOWING GINGIVECTOMY/GINGIVOPLASTY PROCEDURES: A PILOT STUDY
Abstract
The study was aimed to determine the efficacy of platelet rich fibrin (PRF), Ozonated olive oil and BlueM Gel application on early wound healing following gingivectomy/gingivoplasty procedures. Method and materials: In this split-mouth study gingivectomy/gingivoplasty procedures performed on 5 patients. The postoperative PRF, Ozonated olive oil and BlueM gel applied areas were compared with control group. The clinical parameters were measured such as: plaque index, gingival index, periodontal probing depth and bleeding on probing at baseline, after IPT & 30 day. The healing of wound determined with H2O2 test, VAS score for pain & LTH index on days 0, 7, 14 & 28th days. Results: On intragroup comparison of PI, GI, PPD, BOP on group1, group2, group3 & group4 shows significant differences in all the four groups at baseline, after IPT and day 30. But on intergroup comparison shows non-significant differences among the four groups at different time intervals; Whereas, VAS, LTH and H2O2 showed significant differences on group1 and group3 showed better results on postoperative days 8, 15 & 30. Conclusion: PRF releases various growth factors and not causes any side effects. Other side ozonated olive oil has antioxidant properties as well as accelerates wound healing, reduced postoperative pain and faster wound healing.
Fields of Study & Subjects
Periodontal Regeneration and Treatments
Medical and Biological Ozone Research
Wound Healing and Treatments
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 31 January 2026
- Language
- EN