EVOLVING EXPLANATION OF AUTO IMMUNE DISEASE – A BRIEF REVIEW

Intermittent fasting which includes periods of fasting and nutrition, has been considered a dietary approach for weight loss and metabolic health improvement. However, its potential benefits in autoimmune diseases have not been widely studied. Autoimmune diseases are chronic conditions characterized by an aberrant immune response against the body's own tissues, leading to inflammation, tissue damage, and functional impairment. The global incidence of autoimmune disorders has shown a significant upward trend, affecting millions and contributing to increased morbidity and healthcare burden. This review describes the common epidemiology, clinical manifestation and mechanisms of autoimmune diseases, with a focus on typical autoimmune diseases including multiple sclerosis, type 1 diabetes, rheumatoid arthritis, systemic lupus erythematosus, and Sjogren’s syndrome. We discuss the current therapeutics developed in this field.