An Interesting Case of Amyloidosis of the Lymph Node: A Case Report and Review of the Literature

Abstract Amyloidosis encompasses a group of diseases characterized by abnormal extracellular deposition of amyloid proteins, which may cause significant organ dysfunction. Light chain (AL) amyloidosis is the most common systemic form of the disease. Here, we present the case of a 74-year-old woman with a rare presentation of lymph node amyloidosis, initially misjudgment as metastatic cancer due to her history of breast carcinoma. The final diagnosis was established through endobronchial ultrasound-guided biopsy (EBUS) and confirmed with histological analysis. She responded well to a combination of immunotherapy and chemotherapy. Keywords: Amyloidosis; Lymph node; AL Amyloidosis; Congo red staining; Lymphadenopathy.