A Review on Role of Nanotechnology in Blood Cancer Treatment

Blood cancer, also known as hematologic cancer, is a group of malignancies that originate in the blood-forming tissues, primarily the bone marrow and lymphatic system. It occurs when abnormal blood cells grow uncontrollably, disrupting the normal production and function of red blood cells, white blood cells, and platelets. These abnormal cells interfere with the body’s ability to fight infection, transport oxygen, and control bleeding. Multiple myeloma, leukemia, and lymphoma are the three common types of blood cancers. Chemotherapy is the major therapy of blood cancers by systemic administration of anticancer agents into the blood. However, a high incidence of relapse often happens, due to the low efficiency of the anticancer agents that accumulate in the tumor site, and therefore lead to a low survival rate of patients. This indicates an urgent need for a targeted drug delivery system to improve the safety and efficacy of therapeutics for blood cancers.the current targeting strategies for blood cancers and recently investigated and approved drug delivery system formulations for blood cancers. current challenges in the application of drug delivery systems for treating blood cancers like Liposomes, dendrimers, microsphere, Quantum dots, & Nanoshells.