MRSI semiLASER pulse sequence for Bruker ParaVision 5.1

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Authors: Zoona Javed, Gary V. Martinez, Miquel E. Cabañas, Silvia Lope‐Piedrafita
Cited by: 0

Abstract

Source code for MRSI semiLASER pulse sequence in Bruker ParaVision 5.1, instructions to compile and deploy the method, and test data sets. The MRSI-semiLASER sequence was implemented in-house on a 7T Bruker Biospec system running ParaVision 5.1, and its performance was compared to the commercially available CSI-PRESS sequence. The results demonstrated that the MRSI-semiLASER sequence achieved improved spatial distribution homogeneity and up to a 1.2-fold increase in SNR compared to CSI-PRESS in murine brain tumors, allowing a 20% reduction in slice thickness without compromising spectral quality. These findings establish the implemented MRSI-semiLASER sequence as a robust tool for high-resolution MRSI acquisition in mouse brain studies, and it is now available for use by interested researchers.

Fields of Study & Subjects

Advanced MRI Techniques and Applications Advanced NMR Techniques and Applications Advanced Neuroimaging Techniques and Applications

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
2 February 2026