MRSI semiLASER pulse sequence for Bruker ParaVision 5.1
Abstract
Source code for MRSI semiLASER pulse sequence in Bruker ParaVision 5.1, instructions to compile and deploy the method, and test data sets. The MRSI-semiLASER sequence was implemented in-house on a 7T Bruker Biospec system running ParaVision 5.1, and its performance was compared to the commercially available CSI-PRESS sequence. The results demonstrated that the MRSI-semiLASER sequence achieved improved spatial distribution homogeneity and up to a 1.2-fold increase in SNR compared to CSI-PRESS in murine brain tumors, allowing a 20% reduction in slice thickness without compromising spectral quality. These findings establish the implemented MRSI-semiLASER sequence as a robust tool for high-resolution MRSI acquisition in mouse brain studies, and it is now available for use by interested researchers.
Fields of Study & Subjects
Advanced MRI Techniques and Applications
Advanced NMR Techniques and Applications
Advanced Neuroimaging Techniques and Applications
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 2 February 2026