3rd_exp_qptiff_from_Spatial immune hubs defined by conserved activated dendritic cells are remodeled by immunotherapy

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Authors: Tomoyuki Minowa
Cited by: 0

Abstract

These QPTIFF files were generated from CODEX multiplexed imaging data. Tissue arrays and sections were stained with validated CODEX antibody panels and processed using the CODEX/PhenoCycler platform (Akoya Biosciences), followed by imaging on a fluorescence microscope (BZ-X series, Keyence Corporation of America). CODEX multiplexed imaging was performed through iterative cycles of fluorophore stripping, oligonucleotide annealing, and imaging, using fluorescently labeled oligonucleotides complementary to antibody-conjugated DNA barcodes. For processed data and downstream analyses, please refer to the related work.

Fields of Study & Subjects

Cancer Immunotherapy and Biomarkers Immunotherapy and Immune Responses Single-cell and spatial transcriptomics

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
25 February 2026
Language
EN