RESULTS OF PHARMACOLOGICAL TREATMENT OF PERIOCULAR SKIN HEMANGIOMAS

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Authors: M. M. Karimov, Khurshida Nurmatova, Marg'uba Mussayeva
Cited by: 0

Abstract

This study investigates the clinical characteristics of infantile hemangiomas located in the periocular region and evaluates the effectiveness of propranolol-based medical therapy. The research was conducted between 2022 and 2026 and included 34 infants, in whom lesion localization, size, and vascular activity were assessed using clinical examination, photographic documentation, and color Doppler ultrasonography. All patients received propranolol at a dose of 1–2 mg/kg/day on an outpatient basis under cardiological monitoring. The results demonstrated a significant reduction in lesion size, blood flow velocity, and vascular activity after treatment (P < 0.05), with early initiation associated with better clinical and hemodynamic outcomes. Color Doppler ultrasonography proved to be a reliable diagnostic tool for evaluating hemangioma activity, monitoring treatment response, and guiding individualized therapeutic strategies.

Fields of Study & Subjects

Vascular Malformations and Hemangiomas Ocular Oncology and Treatments Vascular Malformations Diagnosis and Treatment

Publication details

Journal / source
Journal of Experimental Studies
Publication date
30 January 2026
Language
UZ