Abiotic Formation of Deoxyribose from Ribose via UV Irradiation and Redox‑Active Clay Surfaces: Quantitative Modeling and Prebiotic Implications(Estimated Calculating Simulation)-(Theoretical Framework)

The origin of deoxyribose, the defining sugar of DNA, remains a central question in prebiotic chemistry. Ribose can form abiotically but is chemically unstable under prebiotic conditions. Here, we present a quantitative, enzyme-free model of UV- and clay-mediated conversion of ribose into deoxyribose. Using experimentally supported degradation rates and an environmental synergy factor (Senv=10–50S_\text{env} = 10–50Senv=10–50), (semi-empirical predictions), we simulate accumulation of deoxyribose. While the model demonstrates plausible trends, key parameters such as the UV conversion rate (kUVk_\text{UV}kUV) and absolute yield remain unmeasured, emphasizing the need for direct laboratory validation. These results are interpreted within the frameworks of Chemical Darwinism and the Matter World Hypothesis (MWH), highlighting a testable prebiotic route for DNA sugar formation.