What are the recommended pharmacological treatments for managing constipation in adults receiving palliative care?
Abstract
Polyethylene glycol (PEG) is the recommended first-line treatment for constipation in palliative care, with stimulant laxatives and PAMORAs like naldemedine used as adjuncts or alternatives, particularly in opioid-induced constipation.
Fields of Study & Subjects
Gastrointestinal motility and disorders
Pain Management and Opioid Use
Pharmaceutical Practices and Patient Outcomes
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 30 January 2026