HORMONAL IMBALANCE AND CAUSES OF FEMALE INFERTILITY: A CLINICAL AND PATHOPHYSIOLOGICAL REVIEW
Abstract
Female infertility is a multifactorial condition frequently associated with hormonal imbalance affecting the hypothalamic–pituitary–ovarian axis. Disorders in endocrine regulation can disrupt ovulation, menstrual regularity, and endometrial receptivity. This article reviews the major hormonal causes of female infertility, including polycystic ovary syndrome, thyroid dysfunction, hyperprolactinemia, luteal phase defects, and metabolic influences. Mechanisms, diagnostic approaches, and current management strategies are discussed. Understanding endocrine-related infertility is essential for early diagnosis and targeted therapy.
Fields of Study & Subjects
Ovarian function and disorders
Reproductive Health and Technologies
Reproductive Biology and Fertility
Publication details
- Journal / source
- International Bulletin of Medical Sciences and Clinical Research
- Publication date
- 3 February 2026
- Language
- EN