Quantitative DIA-based proteomic analysis of lysosomes (Lyso-IP) from VPS35[D620N] Mouse Lung with LRRK2 inhibition

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Authors: Yuko P. Y. Lam, Emily A. Dickie
Cited by: 0

Abstract

This Zenodo deposit contains a publicly available description of the Dataset: Title: "Quantitative DIA-based proteomic analysis of lysosomes (Lyso-IP) from VPS35[D620N] Mouse Lung with LRRK2 inhibition". Description: Proteomic analysis of lung lysosomes from VPS35[D620N] mice treated in vivo with MLi-2 (100 mg/kg, 2 h). Data acquired on an Orbitrap Exploris 480 and processed using DIA-NN 1.8.1. This dataset is made available to researchers via the ASAP CRN Cloud: cloud.parkinsonsroadmap.org. Instructions for how to request access can be found in the User Manual. This research was funded by the Aligning Science Across Parkinson's Collaborative Research Network (ASAP CRN), through the Michael J. Fox Foundation for Parkinson's Research (MJFF). This Zenodo deposit was created by the ASAP CRN Cloud staff on behalf of the dataset authors. It provides a citable reference for a CRN Cloud Dataset

Fields of Study & Subjects

Parkinson's Disease Mechanisms and Treatments Advanced Proteomics Techniques and Applications Autophagy in Disease and Therapy

Publication details

Journal / source
Discovery Research Portal (University of Dundee)
Publication date
31 January 2026
Document type
Dataset