singIST: an integrative method for comparative single-cell transcriptomics between disease models and humans
Abstract
The data contained in this repository include the preprocessed Seurat objects obtained from the original publications for which distribution permission has been secured. These Seurat objects enable full reproducibility of the analyses. In addition, the repository provides the output objects from the singIST workflow for the Atopic Dermatitis (AD) and Hidradenitis Suppurativa (HS) use cases: the optimal asmbPLS-DA fit object and the singIST recapitulations object. For contact matters for the HS data contact Prof. Dr. Johann Gudjonsson (johanng@med.umich.edu) and Prof. Dr. Alex Tsoi (alextsoi@med.umich.edu). For contact matters for the AD data contact Mr. Aitor Moruno-Cuenca (aitor.morunocuenca@almirall.com)
Fields of Study & Subjects
Single-cell and spatial transcriptomics
Dermatology and Skin Diseases
Gene expression and cancer classification
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 4 February 2026
- Document type
- Dataset