An HERV-LTR associating transcript is silenced completely immediately prior to TE commitment in human pluripotent stem cells.

Zenodo (CERN European Organization for Nuclear Research) 2026 Preprint Open access

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Authors: Shahan Mamoor
DOI: 10.5281/zenodo.18487734
Cited by: 0

Abstract

We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here identification of an HERV-LTR associating transcript cooperating factor in lineage commitment of embryonic stem cells of the human embryo.

Fields of Study & Subjects

Pluripotent Stem Cells Research Developmental Biology and Gene Regulation Epigenetics and DNA Methylation

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
4 February 2026
Document type
Preprint