What are the long-term effects of spironolactone?

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Authors: Tripdatabase
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Abstract

Spironolactone provides long-term cardiovascular and renal benefits, but side effects like hyperkalaemia and gynecomastia are significant considerations. Further research on diverse populations is needed to strengthen the safety and efficacy profile.

Fields of Study & Subjects

Hormonal Regulation and Hypertension Potassium and Related Disorders Blood Pressure and Hypertension Studies

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
4 February 2026