Mechanical effect of vocal fold nodules on phonation - Physical and computational modeling approach

These datasets provide supporting materials for the manuscript titled "Mechanical effect of vocal fold nodules on phonation - Physical and computational modeling approach." To understand the mechanical effect of the vocal fold (VF) nodules on phonation and to study how the size and stiffness of the nodules influence the VF oscillations, physical model experiments were carried out. The model was based on the magnetic resonance imaging (MRI) model of the VFs, the geometry of which was scanned from an MRI of a human larynx. As a model for the nodule, hemispherical object was inserted between the cover and epithelium layers of the VF. To study how the characteristics of the nodule influenced the vocalization, the size and the stiffness were varied. For each setting of the nodule size and stiffness, 3 model instances were fabricated and used for the flow experiment. The phonation onset pressure was measured by slowly increasing the flow-rate from 0 l/min to a maximal value in 5 sec, kept to the maximal level for 10 sec, and then decreased to 0 l/min in 5 sec. Here, the maximal airflow was set to be about 1.5 times of the pre-measured onset airflow. The experiments were repeated three times for each instance. XLSX files contain simultaneous measurements of microphone signal, sound pressure level (SPL), subglottal pressure, and flow-rate (sampling frequency: 12.5 kHz). The MP4 files contain high-speed measurements of the dynamics of the MRI model (10000 fps). 1 MRI_normal.xlsx, MRI_normal_1.mp4 No nodules were attached to the VFs. 2.1 MRI_15k.xlsx, MRI_15k_1.mp4 The diameter of the nodule was set to 1.5 mm, whereas the nodule stiffness was set to 102.5 kPa (DS 1:1:1). 2.2 MRI_20k.xlsx, MRI_20k_1.mp4 The diameter of the nodule was set to 2.0 mm, whereas the nodule stiffness was set to 102.5 kPa (DS 1:1:1). 2.3 MRI_25k.xlsx, MRI_25k_1.mp4 The diameter of the nodule was set to 2.5 mm, whereas the nodule stiffness was set to 102.5 kPa (DS 1:1:1). 2.4 MRI_30k.xlsx, MRI_30k_1.mp4 The diameter of the nodule was set to 3.0 mm, whereas the nodule stiffness was set to 102.5 kPa (DS 1:1:1). 3.1 MRI_EF114.xlsx, MRI_EF114_1.mp4 The nodule stiffness was set to 5.8 kPa (EF 1:1:4), whereas the nodule diameter was fixed to 3.0 mm. 3.2 MRI_EF112.xlsx, MRI_EF112_1.mp4 The nodule stiffness was set to 13.2 kPa (EF 1:1:2), whereas the nodule diameter was fixed to 3.0 mm. 3.3 MRI_DS112.xlsx, MRI_DS112_1.mp4 The nodule stiffness was set to 54.7 kPa (DS 1:1:2), whereas the nodule diameter was fixed to 3.0 mm. 3.4 MRI_DS111.xlsx, MRI_DS111_1.mp4 The nodule stiffness was set to 102.5 kPa (DS 1:1:1), whereas the nodule diameter was fixed to 3.0 mm.