Single-Cell Biofilm Heterogeneity Pilot

Read full text
Authors: Almotasem Bellah Younis
Cited by: 0

Abstract

Reanalysis of bacterial single-cell RNA-seq data (GSE231935, M3-Seq) demonstrating transcriptional heterogeneity in E. coli populations. Pipeline: load, QC, normalize, PCA/UMAP, clustering, differential expression. Findings support future work on biofilm regulation and MGE-host interactions.

Fields of Study & Subjects

Bacterial biofilms and quorum sensing Single-cell and spatial transcriptomics Bacterial Genetics and Biotechnology

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
5 February 2026