Single-Cell Biofilm Heterogeneity Pilot
Abstract
Reanalysis of bacterial single-cell RNA-seq data (GSE231935, M3-Seq) demonstrating transcriptional heterogeneity in E. coli populations. Pipeline: load, QC, normalize, PCA/UMAP, clustering, differential expression. Findings support future work on biofilm regulation and MGE-host interactions.
Fields of Study & Subjects
Bacterial biofilms and quorum sensing
Single-cell and spatial transcriptomics
Bacterial Genetics and Biotechnology
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 5 February 2026