A Systemic Review on Calanthe Trulliformis

Calanthe species is a Tujia ethnic herb, which has traditionally been used to treat gastric ulcers, chronic hepatitis, etc. We explored the chemical constitutes, gastroprotective effects, and the active fraction of C. species , as well as elucidating the underlying mechanisms. Firstly, four in vitro antioxidant tests were applied to determine the oxidation resistance of C. species methanol extract and its fractions. The gastroprotective effects were evaluated in ethanol-induced gastric ulcer rats, gastric histopathology was visualized by H&E staining, and the acidity of gastric juice was measured by titrating with NaOH solution. The contents of malondialdehyde, catalase, superoxide dismutase, gastroinstetinal, and the activity of H+K+-ATPase were estimated using commercial kits. For the first time, all of these compounds were extracted from C. Species . The findings showed that CsEF is a promising source of gastroprotective agents; the underlying mechanism of action was found to be the antioxidant activity of this herb, along with the prevention of gastrin secretion and inhibition of H+K+-ATPase.