Prevention of Thrombosis of Central Venous Hemodialysis Catheters

Abstract Introduction: Central venous catheter thrombosis is a frequent complication in hemodialysis responsible for catheter dysfunction which most often requires its removal and the insertion of a new catheter. Objective: To develop an effective preventive strategy for thrombosis of central venous hemodialysis catheters. Material and Methods: We carried out a tri-centric prospective study concerning the prevention of thrombosis of hemodialysis catheters. We compared the effectiveness of a lock based on a mixture of low molecular weight heparin and standard heparin with a conventional lock based on standard heparin alone. Results: Our study demonstrated remarkable effectiveness of the lock based on a mixture of low molecular weight heparin and standard heparin in the prevention of thrombosis of hemodialysis catheters with an extension of the duration of use of the catheter without noting any cases of hemorrhagic syndrome. Conclusion: Despite the limited size of our study, it was able to demonstrate satisfactory and significantly better efficacy in the prevention of thrombosis of hemodialysis catheters.