Role of Trace Elements in Clinical Care

📄 Resource Shared: Microns with Macro Impact – Trace Elements in Critical Care I am sharing the complete slide deck from my recent session, "Microns with Macro Impact: The Physiology, Pathology, and Practice of Trace Elements in Critical Illness." This presentation moves beyond the "macro" management of ICU patients to explore the molecular "invisible engineers" that regulate survival. It addresses the Goldilocks Paradox of trace element management—where too little is fatal, but too much is toxic. Key topics covered in this deck: • The "False Low" Phenomenon: Understanding why inflammation (CRP > 20 mg/L) causes a physiological redistribution of Zinc and Selenium, mimicking deficiency. • The "Leaking Bucket": How to manage iatrogenic losses from CRRT, burns, and medications. • Clinical Detective Work: Visual guides for spotting Acrodermatitis (Zinc), Keshan Disease (Selenium), and neurological mimics (Copper/Manganese). • Updated Protocols: A clinical decision matrix for supplementation in sepsis, trauma, and organ failure. 🔗 Access the full presentation via DOI: 10.5281/zenodo.18518013