Review on Ovarian Cancer
Abstract
Ovarian cancer is a deadly gynecologic cancer, often diagnosed late due to vague symptoms, leading to poor survival, but improved treatments like surgery, platinum chemo, and targeted drugs (PARP inhibitors, bevacizumab) are increasing survival, especially with genetic awareness (BRCA mutations). Most cases (90%) are epithelial, primarily high-grade serous, with key risk factors being age, genetics (BRCA1/2), family history, and nulliparity, while oral contraceptives and childbirth reduce risk. Treatment involves cytoreductive surgery and chemotherapy, with maintenance targeted therapies and new approaches for recurrence.
Fields of Study & Subjects
Ovarian cancer diagnosis and treatment
BRCA gene mutations in cancer
PARP inhibition in cancer therapy
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 8 February 2026