A Comprehensive Review on Annona squamosa Loaded Bio Patches

Bio patches are a revolutionary approach in transdermal drug delivery system, providing controlled and sustained release of active pharmaceutical ingredients to improve patient compliance Annono squamosa also known as (custard apple) a medicinal plant which are rich in bioactive compound like alkaloids, flavonoids, and acetogenins. That are show various pharmacological activities such as antimicrobial, anti-inflammatory, antioxidant, and anticancer effects. In this review we are explore the integration of Annona squamosa into bio patches and focusing on its phytochemical properties, extraction methods, formulation techniques, characterization methods, therapeutic applications advantages and disadvantages. the review discusses Transdermal Drug Delivery Systems, Controlled and Sustained Release, challenges and future prospects, of Annona squamosa-loaded bio patches in innovative drug delivery systems.