Diversity of Cortical Progenitors Directs Neuronal Layer Formation and Regional Glial Patterning

Read full text
Authors: Ana Cristina Ojalvo‐Sanz, María Figueres‐Oñate, Sonsoles Barriola, Carolina Pernia‐Solanilla, Rebeca Sánchez‐González, Lina Maria Delgado Garcia, Laura López‐Mascaraque
Cited by: 0

Abstract

This dataset contains bulk RNA-seq data from GFP⁺ NG2⁺ or GFAP⁺ cells isolated by FACS following StarTrack labeling by in utero electroporation (IUE) at embryonic day E12, with cortical tissue dissociated at E14. A total of 10 samples are included (5 NG2⁺ and 5 GFAP⁺ biological replicates). An Excel file (data_counts_fpkm) is provided containing gene-level raw read counts (*_count) and normalized expression values (*_fpkm) for each replicate. The file also includes differential expression analysis results for NG2 vs GFAP and GFAP vs NG2 comparisons (log2 fold change, p-values, and adjusted p-values), as well as gene annotations including gene name, chromosomal location, strand, gene length, biotype, functional description, and transcription factor family. Raw sequencing data are provided as paired-end compressed FASTQ files (.fq.gz), where _1 and _2 correspond to forward (R1) and reverse (R2) reads from the same biological sample.

Fields of Study & Subjects

Neurogenesis and neuroplasticity mechanisms Developmental Biology and Gene Regulation Congenital heart defects research

Publication details

Journal / source
DIGITAL.CSIC (Spanish National Research Council (CSIC))
Publication date
9 February 2026
Language
EN
Document type
Dataset