Diversity of Cortical Progenitors Directs Neuronal Layer Formation and Regional Glial Patterning
Abstract
This dataset contains bulk RNA-seq data from GFP⁺ NG2⁺ or GFAP⁺ cells isolated by FACS following StarTrack labeling by in utero electroporation (IUE) at embryonic day E12, with cortical tissue dissociated at E14. A total of 10 samples are included (5 NG2⁺ and 5 GFAP⁺ biological replicates). An Excel file (data_counts_fpkm) is provided containing gene-level raw read counts (*_count) and normalized expression values (*_fpkm) for each replicate. The file also includes differential expression analysis results for NG2 vs GFAP and GFAP vs NG2 comparisons (log2 fold change, p-values, and adjusted p-values), as well as gene annotations including gene name, chromosomal location, strand, gene length, biotype, functional description, and transcription factor family. Raw sequencing data are provided as paired-end compressed FASTQ files (.fq.gz), where _1 and _2 correspond to forward (R1) and reverse (R2) reads from the same biological sample.
Fields of Study & Subjects
Neurogenesis and neuroplasticity mechanisms
Developmental Biology and Gene Regulation
Congenital heart defects research
Publication details
- Journal / source
- DIGITAL.CSIC (Spanish National Research Council (CSIC))
- Publication date
- 9 February 2026
- Language
- EN
- Document type
- Dataset