Can amitriptyline be taken with sertraline?

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Authors: Tripdatabase
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Abstract

Amitriptyline can be coadministered with sertraline, but this combination should be approached with caution due to potential drug interactions that may increase the risk of side effects.

Fields of Study & Subjects

Treatment of Major Depression Pharmacogenetics and Drug Metabolism Pharmacovigilance and Adverse Drug Reactions

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
9 February 2026