Silencing of an unannotated gene product, LOC101928499 occurs progressively during differentiation to the trophectoderm in the human embryo.
Abstract
We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here discovery of LOC101928499 as a lineage commitment factor or lineage commitment cooperating factor in embryonic stem cells of the human embryo.
Fields of Study & Subjects
Pluripotent Stem Cells Research
Developmental Biology and Gene Regulation
Epigenetics and DNA Methylation
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 9 February 2026
- Document type
- Preprint