Phospholipase signaling during TE specification in the human embryo.
Abstract
We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here identification of multiple components of the phospholipid signaling pathway as lineage commitment cooperating factor in embryonic stem cells of the human embryo. Relevant components included DGKK, ITPR2 and Pla2g4f.
Fields of Study & Subjects
Pluripotent Stem Cells Research
Developmental Biology and Gene Regulation
Reproductive Biology and Fertility
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 9 February 2026
- Language
- EN
- Document type
- Preprint