A retrotransposon-like gene, RTL5, is modulated during differentiation of embryonic stem cells to the trophectoderm lineage.

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Authors: Shahan Mamoor
Cited by: 0

Abstract

We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here discovery of a retrotransposon-like gene, RTL5, with putative functions in lineage commitment in embryonic stem cells of the human embryo.

Fields of Study & Subjects

Pluripotent Stem Cells Research Developmental Biology and Gene Regulation Epigenetics and DNA Methylation

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
9 February 2026
Document type
Preprint