A retrotransposon-like gene, RTL5, is modulated during differentiation of embryonic stem cells to the trophectoderm lineage.
Abstract
We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here discovery of a retrotransposon-like gene, RTL5, with putative functions in lineage commitment in embryonic stem cells of the human embryo.
Fields of Study & Subjects
Pluripotent Stem Cells Research
Developmental Biology and Gene Regulation
Epigenetics and DNA Methylation
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 9 February 2026
- Document type
- Preprint